How does emetrol (domperidone) work on the human body

Emetrol (domperidone) is a dopamine antagonist with antiemetic properties. Emetrol poorly penetrates the blood-brain barrier (BBB). The use of domperidone is very rarely accompanied by extrapyramidal side effects, especially in adults, but domperidone stimulates prolactin production by the pituitary gland. Its antiemetic effect may be due to a combination of peripheral (gastrokinetic) action and antagonism

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